湖南大学“岳麓材料杰出学者论坛”第278期
题 目：Novel Bioceramics as Promising Materials for Bone Tissue Engineering
报告人：Dr. Eng San Thian
地 点：中三栋205会议室
时 间：2024年10月28（周一）19:00-20:00
主持人： 王祖勇
邀请人：材料科学与工程学院
报告摘要：
The development of novel functional biomaterial with improved biomimicry will provide appropriate signaling that is capable of controlling tissue regeneration, to ensure 'appropriate fit' with the intended final applications. Substitution of a single element into hydroxyapatite (HA) is commonly performed to improve its biological properties. However, co-substitution of two or more elements is uncommon, and is not easily achieved due to the ionic size difference between elements as well as the instability of HA. Despite the favourable biological response of HA for bone repair, it has a slow rate of bone apposition and lacks of antibacterial properties. The development of silver,silicon co-substituted HA (Ag,Si-HA) as a novel bi-functional biomaterial, with optimum amount of Ag and Si, has shown to reduce bacterial colonisation and enhance osteogenic properties, respectively; thus addressing the shortcomings of commercially available HA and SiHA. Moving forward, Ag,Si-HA can potentially be used as a promising alternative bone graft material for musculoskeletal applications.
报告人简介：
Dr. Eng San Thian presently holds the position of Associate Professor of Biomaterials in the Department of Mechanical Engineering at the National University of Singapore. He attained his his Ph.D degree in Natural Sciences at the Department of Materials Science and Metallurgy at the University of Cambridge in the United Kingdom. Dr. Thian’s research interests span a wide range of areas including (but not limited to) nanobiomaterials, surface modifications, tissue engineering, and the enhancement of food security. Dr. Thian is actively involved in cutting-edge research that tackles significant healthcare and food packaging issues on a global scale. He has significantly advanced the biomaterials field, with a publication record of over 100 journal papers, conference papers, and book chapters. He has graduated more than 14 Ph.D/M.Eng students, and successfully garnered over S$11 million in research funding. Moreover, Dr. Thian contributes to the scientific community as an Associate Editor-in-Chief or as a valued member of the editorial board for several renowned international journals. In recognition of his exceptional contributions to the field, Dr. Thian has been honoured with the title of Fellow of the Institute of Materials, Minerals and Mining (FIMMM) and at the same time, earned a Hitachi Research Fellowship to further his research in Japan. His dedication to teaching has been recognized multiple times with University or College -level teaching awards. Recently, in recognition of his community service contributions and leadership, he was awarded the Public Service Medal (PBM) by the President of the Republic of Singapore.
